The nearest airport are Madurai and Tiruchirappalli about 98 kms away from Karaikudi.
The train services are available to Sivagangai, Manamadurai, Paramakudi, Ramanathapuram, Mandapam, Rameshwaram, Aruppukottai, Virudhunagar, Rajapalayam, Kollam, Tiruchirappallai, Tanjore, Velankanni, Nagoor and Chennai from this town.
From the Manamadurai Junction (65 k.m. from here) services are also available to Madurai, Dindigul, Palani, Coimbatore, Palakkadu.
Government Transport Corporations play number of buses. Private transports and mini bus services are also operated day and night. Bus stand with all its facilities is housed in the heart of the town. There is a good transport net work system in the town. Regular bus services are available to all important cities of Tamil Nadu, Kumuli of Kerala state and Bangalore of Karnataka state from this town.